Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 7/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167911 | 0.90 | L3MBTL1 (0.37) | KDM4EALDH1A1HPGDHSD17B10HTR2B | |
| SCHEMBL6167825 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10HTR2B | |
| SCHEMBL6167533 | 0.86 | HPGDS (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR2B | |
| SCHEMBL6166850 | 0.82 | HRH2 (0.35) | KDM4EHTR2BATML3MBTL1 | |
| SCHEMBL2834139 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10HTR2B | |
| SCHEMBL6166813 | 0.81 | MIF (0.41) | KDM4EALDH1A1HPGDHTR2BL3MBTL1 | |
| SCHEMBL6166739 | 0.80 | CHRM2 (0.37) | KDM4EALDH1A1P2RY12ATML3MBTL1 | |
| SCHEMBL6167913 | 0.79 | TRPC6 (0.34) | — | |
| SCHEMBL6166994 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10P2RY12 | |
| SCHEMBL6168951 | 0.78 | HTR2B (0.51) | HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |