Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166739 | 0.91 | CHRM2 (0.37) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6166202 | 0.86 | LMNA (0.40) | KDM4ETP53HSD17B10MAPTLMNA | |
| SCHEMBL6166805 | 0.81 | TRPV1 (0.35) | KDM4ETP53HSD17B10MAPTLMNA | |
| SCHEMBL6167911 | 0.80 | L3MBTL1 (0.37) | KDM4EHSD17B10ALDH1A1L3MBTL1HPGD | |
| SCHEMBL6166850 | 0.79 | HRH2 (0.35) | KDM4ETP53MAPTL3MBTL1MAPK1 | |
| SCHEMBL6167913 | 0.79 | TRPC6 (0.34) | MAPTMEN1KMT2APOLBTRPC3 | |
| SCHEMBL17396055 | 0.78 | GCK (0.42) | KDM4ETP53HSD17B10MAPTLMNA | |
| SCHEMBL6167984 | 0.78 | P2RY12 (0.44) | — | |
| SCHEMBL6166634 | 0.76 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6169490 | 0.75 | GRM5 (0.45) | KDM4EMAPTLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |