Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167911 | 0.91 | L3MBTL1 (0.37) | HTR2BALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL6166850 | 0.90 | HRH2 (0.35) | MIFHTR2BKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6167913 | 0.89 | TRPC6 (0.34) | POLBMAPTHRH2HRH1 | |
| SCHEMBL6164853 | 0.87 | HTT (0.46) | MIFHTR2BHTTCYP1A2POLB | |
| SCHEMBL6168913 | 0.81 | KDM4E (0.41) | HTR2BALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL6166739 | 0.80 | CHRM2 (0.37) | ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6166218 | 0.80 | KDM4E (0.36) | HTTCYP1A2POLBCYP3A4CYP2D6 | |
| SCHEMBL6168935 | 0.78 | HTR2B (0.48) | HTR2BHTTPOLBALDH1A1HPGD | |
| SCHEMBL6166994 | 0.77 | KDM4E (0.46) | ALDH1A1HPGDKDM4E | |
| SCHEMBL6165607 | 0.76 | HRH2 (0.45) | HTTPOLBALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |