Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167911 | 0.92 | L3MBTL1 (0.37) | P2RY14KDM4EIGF1RMAPK1L3MBTL1 | |
| SCHEMBL6166813 | 0.90 | MIF (0.41) | HRH2HRH1MAPTKDM4EMIF | |
| SCHEMBL6167913 | 0.88 | TRPC6 (0.34) | HRH2HRH1P2RY14MAPTBTK | |
| SCHEMBL6165607 | 0.87 | HRH2 (0.45) | HRH2HRH1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL6168913 | 0.82 | KDM4E (0.41) | ATMKDM4EL3MBTL1HTR2B | |
| SCHEMBL6166739 | 0.81 | CHRM2 (0.37) | ATMKDM4EIGF1RMAPK1L3MBTL1 | |
| SCHEMBL6166218 | 0.79 | KDM4E (0.36) | MAPTTP53KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL6166994 | 0.78 | KDM4E (0.46) | KDM4E | |
| SCHEMBL6164853 | 0.76 | HTT (0.46) | HRH2HRH1MAPTKDM4EMIF | |
| SCHEMBL6168057 | 0.75 | MEN1 (0.41) | HRH2HRH1MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |