Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 10/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166218 | 0.91 | KDM4E (0.36) | CHRM3L3MBTL1KDM4EMAPK1MEN1 | |
| SCHEMBL6167911 | 0.89 | L3MBTL1 (0.37) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6167984 | 0.86 | P2RY12 (0.44) | P2RY12 | |
| SCHEMBL6167867 | 0.81 | CPT1A (0.38) | P2RY12L3MBTL1 | |
| SCHEMBL6166850 | 0.81 | HRH2 (0.35) | L3MBTL1KDM4EMAPK1ATMIGF1R | |
| SCHEMBL6166813 | 0.80 | MIF (0.41) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6166994 | 0.80 | KDM4E (0.46) | P2RY12KDM4EALDH1A1 | |
| SCHEMBL6168913 | 0.80 | KDM4E (0.41) | P2RY12L3MBTL1KDM4EATMALDH1A1 | |
| SCHEMBL6167913 | 0.79 | TRPC6 (0.34) | CHRM3MEN1KMT2AHRH3 | |
| SCHEMBL6166202 | 0.78 | LMNA (0.40) | P2RY12L3MBTL1KDM4EMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349850-B1 | SODIUM CHANNEL MODULATORS DERIVED FROM 2-PIPERIDYLIMIDAZOLES | SOD CONSEILS RECH APPLIC (FR) | 2005-09-07 | — | — | EP | claimed |