Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167721 | 0.84 | HTT (0.48) | HTT | |
| SCHEMBL6164339 | 0.76 | HTT (0.34) | HTT | |
| SCHEMBL6162649 | 0.69 | PARP1 (0.37) | — | |
| SCHEMBL6167036 | 0.66 | RIPK3 (0.39) | — | |
| SCHEMBL6166684 | 0.64 | MAOB (0.33) | — | |
| SCHEMBL6166686 | 0.64 | MAOB (0.33) | — | |
| SCHEMBL6165490 | 0.64 | LMNA (0.49) | HTT | |
| SCHEMBL6167558 | 0.64 | BRD4 (0.31) | — | |
| SCHEMBL6165983 | 0.64 | ATM (0.44) | — | |
| SCHEMBL6166254 | 0.64 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177185-B1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2005-04-20 | — | — | EP | disclosed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |