Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167711 | 0.89 | CNR1 (0.50) | LMNACNR1MMP2MMP9MGLL | |
| SCHEMBL6168870 | 0.86 | GAA (0.46) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL6169738 | 0.85 | CNR1 (0.43) | LMNAKDM4EMEN1KMT2ACNR1 | |
| SCHEMBL6168712 | 0.82 | CNR1 (0.46) | MAPTMEN1KMT2ACNR1MMP2 | |
| SCHEMBL6625449 | 0.78 | MAPT (0.47) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6168455 | 0.78 | PGR (0.41) | LMNAMEN1KMT2ACNR1MMP2 | |
| SCHEMBL6167462 | 0.78 | CNR1 (0.41) | LMNACNR1MMP2MMP9MGLL | |
| SCHEMBL6170632 | 0.77 | ALDH1A1 (0.46) | MAPTMMP13ALDH1A1SMN1; SMN2 | |
| SCHEMBL7481341 | 0.77 | CNR1 (0.55) | LMNAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL6170930 | 0.76 | HSD11B1 (0.44) | LMNAKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |