Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 3/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6167711 | 0.83 | CNR1 (0.50) | ALDH1A1HTTDYRK1BMMP13GAA | |
| SCHEMBL6624503 | 0.82 | MAPT (0.54) | ALDH1A1CRHBPCRHR2CMA1DYRK1A | |
| SCHEMBL6168870 | 0.81 | GAA (0.46) | ALDH1A1MAPTMMP13GAASMN1; SMN2 | |
| SCHEMBL6169738 | 0.80 | CNR1 (0.43) | ALDH1A1HTTMMP13GAA | |
| SCHEMBL6168455 | 0.79 | PGR (0.41) | ALDH1A1HTTCRHBPCRHR2OPRM1 | |
| SCHEMBL6168079 | 0.77 | LMNA (0.47) | ALDH1A1MAPTMMP13SMN1; SMN2 | |
| SCHEMBL6168712 | 0.76 | CNR1 (0.46) | ALDH1A1DYRK1BMAPTMMP13GAA | |
| SCHEMBL6167462 | 0.75 | CNR1 (0.41) | ALDH1A1HTTMMP13GAASMN1; SMN2 | |
| SCHEMBL5955277 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HTTNPSR1CMA1MAPT | |
| SCHEMBL6170930 | 0.71 | HSD11B1 (0.44) | ALDH1A1HTTNPSR1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546111-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031160-A2 | 2-THIOHYDANTOINE DERIVATIVE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-04-15 | — | — | WO | disclosed |