Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171157 | 0.88 | PLA2G2A (0.49) | PLA2G2AMAPTRAB9AMEN1KMT2A | |
| SCHEMBL6170807 | 0.81 | LMNA (0.50) | MAPTMAPK8MEN1KMT2AAXL | |
| SCHEMBL9896760 | 0.80 | PLA2G2A (0.53) | PLA2G2AMAPTRAB9AMAPK8MEN1 | |
| SCHEMBL9898507 | 0.79 | NR4A2 (0.50) | MAPTRAB9AMAPK8MEN1KMT2A | |
| SCHEMBL20772780 | 0.77 | ALDH1A1 (0.55) | RAB9AKMT2AGAAKCNA5ALDH1A1 | |
| SCHEMBL6170862 | 0.76 | CNR2 (0.44) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1334120 | 0.76 | DHODH (0.46) | PLA2G2AMAPTMEN1KMT2AGAA | |
| SCHEMBL30128969 | 0.76 | DHODH (0.46) | PLA2G2AMAPTMEN1KMT2AGAA | |
| SCHEMBL17733182 | 0.76 | FABP3 (0.47) | PLA2G2AMAPTRAB9AMAPK8MEN1 | |
| SCHEMBL6169984 | 0.76 | RAB9A (0.40) | PLA2G2AMAPTRAB9AMAPK8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112263-B1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1112263-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6113814-A | PHOTOCHROMIC; END-CAPPED WITH A POLYMERIZABLE GROUP. | TRANSITIONS OPTICAL, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-2000015629-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |