Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6170797 | 0.81 | APP (0.47) | MEN1KMT2AKDM4EAPPALDH1A1 | |
| SCHEMBL719359 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28673732 | 0.73 | APP (0.46) | MEN1KMT2AAPPALDH1A1LMNA | |
| SCHEMBL9440336 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10018185 | 0.70 | PTPN5 (0.44) | KMT2AKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4614660 | 0.70 | NR1I2 (0.37) | KMT2AALDH1A1POLB | |
| SCHEMBL4612178 | 0.70 | SMN1; SMN2 (0.41) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL14009519 | 0.70 | DRD2 (0.41) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8794322 | 0.70 | ALDH1A3 (0.50) | MEN1KMT2AAPPALDH1A1LMNA | |
| SCHEMBL1011203 | 0.69 | KIF11 (0.45) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112263-B1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-06-08 | — | — | EP | disclosed |
| US-6113814-A | PHOTOCHROMIC; END-CAPPED WITH A POLYMERIZABLE GROUP. | TRANSITIONS OPTICAL, INC. (US) | 2000-09-05 | — | — | US | disclosed |