Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719359 | 0.91 | ALDH1A1 (0.55) | ALDH1A1RECQLSMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL28673732 | 0.88 | APP (0.46) | APPALDH1A1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL6170793 | 0.81 | MEN1 (0.35) | APPALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL28365758 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL9933229 | 0.81 | LTA4H (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7815315 | 0.80 | L3MBTL1 (0.40) | APPALDH1A1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL24678322 | 0.78 | CYP3A4 (0.49) | ALDH1A1RECQLSMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL1815976 | 0.78 | CYP3A4 (0.49) | APPALDH1A1RECQLSMN1; SMN2CYP3A4 | |
| SCHEMBL1817358 | 0.78 | SMN1; SMN2 (0.45) | APPALDH1A1RECQLSMN1; SMN2CYP3A4 | |
| SCHEMBL1812486 | 0.78 | KIF11 (0.49) | ALDH1A1SMN1; SMN2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112263-B1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1112263-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6113814-A | PHOTOCHROMIC; END-CAPPED WITH A POLYMERIZABLE GROUP. | TRANSITIONS OPTICAL, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| WO-2000015629-A1 | POLYMERIZABLE POLYALKOXYLATED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-23 | — | — | WO | disclosed |