Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL6491084 | 0.95 | LMNA (0.43) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL23919140 | 0.95 | LTA4H (0.53) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL25954061 | 0.93 | ELANE (0.46) | LTA4HLMNASMN1; SMN2CES2CES1 | |
| SCHEMBL164160 | 0.93 | ELANE (0.46) | LTA4HLMNASMN1; SMN2CES2CES1 | |
| SCHEMBL31493151 | 0.91 | KIF11 (0.39) | KIF11KCNH2CA4LTA4HLMNA | |
| SCHEMBL25954066 | 0.90 | ELANE (0.40) | KIF11KCNH2LMNAHTTSMN1; SMN2 | |
| SCHEMBL10106949 | 0.88 | LTA4H (0.62) | LTA4HLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL25954105 | 0.87 | ESR2 (0.48) | SMN1; SMN2ELANE | |
| SCHEMBL25954108 | 0.87 | LTA4H (0.48) | LTA4HLMNAHTTSMN1; SMN2KMT2A | |
| SCHEMBL25954134 | 0.87 | ELANE (0.42) | LTA4HLMNASMN1; SMN2KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12247035-B2 | Articles comprising indolenaphthopyrans | TRANSITIONS OPTICAL, LTD. (IE) | 2025-03-11 | — | — | US | disclosed |
| US-20250018065-A1 | HIGH-INTENSITY FOCUSED ULTRASOUND-INDUCED MECHANOCHEMICAL TRANSDUCTION IN SYNTHETIC ELASTOMERS | The Brd. of Trustees of the Univ. of Illinois (US) | 2025-01-16 | — | — | US | disclosed |
| EP-3898635-B1 | ARTICLES COMPRISING INDOLONAPHTHOPYRANS | TRANSITIONS OPTICAL LTD (IE) | 2024-12-04 | — | — | EP | disclosed |
| US-12121597-B2 | High-intensity focused ultrasound-induced mechanochemical transduction in synthetic elastomers | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-10-22 | — | — | US | disclosed |
| CN-112313210-B | Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence | 光学转变有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-113150007-B | Photochromic indeno-fused ring pyran compounds | 光学转变公司 | 2024-03-08 | — | — | CN | disclosed |
| US-11874434-B2 | Ophthalmic devices comprising photochromic materials with reactive substituents | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| EP-3898636-B9 | INDOLONAPHTHOPYRANS | TRANSITIONS OPTICAL LTD (IE) | 2023-11-08 | — | — | EP | disclosed |
| EP-3898636-B1 | INDOLONAPHTHOPYRANS | TRANSITIONS OPTICAL LTD (IE) | 2023-08-30 | — | — | EP | disclosed |
| US-11518751-B2 | Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence | TRANSITIONS OPTICAL, LTD. (IE) | 2022-12-06 | — | — | US | disclosed |
| US-5384077-A | Naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 1995-01-24 | — | — | US | disclosed |
| WO-1995000866-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| EP-0613475-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1994-09-07 | — | — | EP | disclosed |
| US-5340857-A | Ophthalmic lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1994-08-23 | — | — | US | disclosed |
| WO-1994007889-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| US-5274132-A | Photochromic naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-5244602-A | Photochromic articles comprising polymerized organic host material and naphthopyran | PPG INDUSTRIES, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1993010112-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1993-05-27 | — | — | WO | disclosed |
| WO-1992009593-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5066818-A | Lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1991-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12121597-B2 | High-intensity focused ultrasound-induced mechanochemical transduction in synthetic elastomers | FUS, PIEZO1, HNRNPUL2 | KIF11 2729/4885KCNH2 4170/4885CA4 1758/4885 |
| US-20250018065-A1 | HIGH-INTENSITY FOCUSED ULTRASOUND-INDUCED MECHANOCHEMICAL TRANSDUCTION IN SYNTHETIC ELASTOMERS | FUS, PIEZO1, HNRNPUL2 | KIF11 2729/4885KCNH2 4170/4885CA4 1758/4885 |
| US-11518751-B2 | Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence | NR2E3, NR0B2, NR2C2 | KIF11 1229/4885KCNH2 919/4885CA4 2584/4885 |
| US-12247035-B2 | Articles comprising indolenaphthopyrans | ACTB, CCNB1, HMBS | KIF11 1333/4885KCNH2 1315/4885CA4 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.