Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447426 | 0.83 | PRKCA (0.36) | PLA2G2A | |
| SCHEMBL6170855 | 0.80 | UNG (0.40) | UNGALDH1A1TRIM24TRIM33TP53 | |
| SCHEMBL7510342 | 0.78 | MEN1 (0.41) | NPC1CYP2C9RAB9AALDH1A1TSHR | |
| SCHEMBL10544293 | 0.66 | SMN1; SMN2 (0.50) | UNGNPC1RAB9AALDH1A1TRIM24 | |
| SCHEMBL2997840 | 0.66 | CES2 (0.48) | UNGNPC1RAB9AALDH1A1TRIM24 | |
| SCHEMBL2773374 | 0.65 | PLA2G2A (0.65) | PLA2G2ATSHRTP53 | |
| SCHEMBL12813482 | 0.64 | KIF11 (0.50) | CYP2C9 | |
| SCHEMBL6172247 | 0.64 | PRKCA (0.38) | NPC1RAB9ATSHRTP53HSD17B10 | |
| SCHEMBL6170678 | 0.62 | TSHR (0.41) | NPSR1RAB9AALDH1A1TSHRKDM4E | |
| SCHEMBL3470017 | 0.62 | UNG (0.61) | UNGALDH1A1TSHRTRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192127-A1 | SUBSTITUTED BENZAMIDE INHIBITORS OF RHINOVIRUS 3C PROTEASE | Agouron Pharmaceuticals, Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000078708-A1 | SUBSTITUTED BENZAMIDE INHIBITORS OF RHINOVIRUS 3C PROTEASE | AGOURON PHARMACEUTICALS, INC. (US) | 2000-12-28 | — | — | WO | disclosed |