SCHEMBL617210

SCHEMBL617210

COc1ccc2ccccc2c1Br

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.64
NCEH1 Q6PIU2 6/20 0.56
NQO1 P15559 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
HPGD P15428 3/20 0.51
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.50
HTT P42858 2/20 0.49
MEN1 O00255 1/20 0.49
TSHR P16473 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP19A1 P11511 1/20 0.49
CYP11B1 P15538 1/20 0.49
CYP11B2 P19099 1/20 0.49
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21331556 0.90 MAPT (0.58) MAPTNCEH1NQO1SMN1; SMN2NPC1
SCHEMBL7380732 0.80 SMN1; SMN2 (0.56) MAPTNCEH1SMN1; SMN2NPC1RAB9A
SCHEMBL29937151 0.80 SMN1; SMN2 (0.56) MAPTNCEH1SMN1; SMN2NPC1RAB9A
SCHEMBL13391169 0.79 MAPT (0.58) MAPTNCEH1SMN1; SMN2NPC1RAB9A
SCHEMBL26622001 0.79 RAB9A (0.55) MAPTNCEH1SMN1; SMN2NPC1RAB9A
SCHEMBL29428410 0.78 MAPT (1.00) MAPTNQO1SMN1; SMN2RAB9AHPGD
SCHEMBL31553099 0.78 CYP19A1 (0.51) MAPTNCEH1NQO1SMN1; SMN2POLB
SCHEMBL998182 0.78 MAPT (1.00) MAPTNQO1SMN1; SMN2RAB9AHPGD
SCHEMBL28862956 0.78 RXFP1 (0.44) MAPTNCEH1NQO1SMN1; SMN2KDM4E
SCHEMBL17086891 0.77 CYP19A1 (0.45) MAPTNQO1CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109305981-B Synthesis method of 2-hydroxynaphthalene-1-boric acid 白银棓诺新材料有限公司 2021-10-29 CN claimed
CN-109305981-A The synthetic method of 2 hydroxy naphthalene -1- boric acid 白银棓诺新材料有限公司 2019-02-05 CN claimed
CN-104507913-A Antiproliferative benzo[b]azepin-2-ones HOFFMANN LA ROCHE 2015-04-08 CN claimed
CN-104470940-A 2-oxo-2,3,4,5-tetrahydro-1 h-benzo[b]diazepines and their use in the treatment of cancer HOFFMANN LA ROCHE 2015-03-25 CN claimed
CN-104470905-A Substituted hetero-azepinones HOFFMANN LA ROCHE 2015-03-25 CN claimed
CN-104418716-A Preparation method of nabumetone intermediate 2-methoxyl-6-naphthaldehyde FUJIAN LIFEIKE BIOTECHNOLOGY CO LTD 2015-03-18 CN claimed
WO-1998050334-A1 PRODUCTION OF BROMINATED METHOXYNAPHTHALENE COMPOUNDS ALBEMARLE CORPORATION (US) 1998-11-12 WO claimed
JP-62142138-A None JP disclosed
JP-10139712-A None JP disclosed
US-20260123269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-04-30 US disclosed
US-12581850-B2 Organic electroluminescence element, composition, powder, electronic equipment, and novel compound IDEMITSU KOSAN CO., LTD. (JP) 2026-03-17 US disclosed
US-20260060000-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2026-02-26 US disclosed
US-20250386661-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2025-12-18 US disclosed
EP-0163338-B1 PROCESS FOR PREPARING NAPROXEN Nobel Chemicals AB (SE) 1987-09-09 EP disclosed
JP-S62142138-A PRODUCTION OF 2-6-METHOXY-2-NAPHTHYL PROPIONIC ACID SANWA KAGAKU KENKYUSHO:KK 1987-06-25 JP disclosed
EP-0221677-A2 p-Aminophenols, derivatives thereof and use for manufacture of a medicament E.R. Squibb & Sons, Inc. (US) 1987-05-13 EP disclosed
EP-0163338-A1 Process for preparing naproxen Nobel Chemicals AB (SE) 1985-12-04 EP disclosed
US-4423244-A Process for the preparation of the d-2-(6-methoxy-2-naphthyl)-propionic acid ALFA CHEMICALS ITALIANA S.P.A. (IT) 1983-12-27 US disclosed
US-3994968-A 2-(5'-Halo-6'-methoxynaphth-2'-yl)-acrylic acid SYNTEX CORPORATION (PM) 1976-11-30 US disclosed
US-3960957-A 2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof SYNTEX CORPORATION (PM) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260123269-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LDLR, MLX MAPT 3924/4885NCEH1 2110/4885NQO1 978/4885
US-20260060000-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE RER1, RIF1, RPS19 MAPT 4037/4885NCEH1 3318/4885NQO1 1286/4885
US-12581850-B2 Organic electroluminescence element, composition, powder, electronic equipment, and novel compound SCO2, SOD1, ITGA1 MAPT 2934/4885NCEH1 2925/4885NQO1 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.