Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 5/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 5/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175493 | 0.79 | PGR (0.41) | MEN1KMT2ANR1I2PGRAR | |
| SCHEMBL6506928 | 0.78 | TRPV4 (0.36) | TRPV4BCAT2BCAT1PGRALDH1A1 | |
| SCHEMBL8195033 | 0.76 | BCAT2 (0.46) | BCAT2BCAT1THRB | |
| SCHEMBL6494272 | 0.76 | BCAT2 (0.38) | TRPV4BCAT2BCAT1PGRALDH1A1 | |
| SCHEMBL5844322 | 0.75 | CYP11B1 (0.39) | MEN1KMT2ATRPV4BCAT2BCAT1 | |
| SCHEMBL9125238 | 0.75 | PGR (0.33) | TRPV4BCAT2BCAT1PGRALDH1A1 | |
| SCHEMBL5841567 | 0.74 | RAB9A (0.42) | MEN1KMT2ATRPV4BCAT2BCAT1 | |
| SCHEMBL10612189 | 0.74 | L3MBTL1 (0.43) | THRB | |
| SCHEMBL7753821 | 0.73 | CYP11B1 (0.41) | MEN1KMT2ATRPV4BCAT2BCAT1 | |
| SCHEMBL8888915 | 0.71 | HPGD (0.39) | MEN1KMT2ATRPV4BCAT2BCAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189893-B1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONE | BAYER CROPSCIENCE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-6608004-B2 | Nitrogen compounds such as 2-(5-(N-phenoxy-carbonyl-N-ethyl-sulphonylamino)-4-cyano-2-fluoro-phenyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione, used as postemergence herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
| US-20030069140-A1 | Substitutes 2-aryl-1,2,4-triazine-3,5-di(thi)one | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-10 | — | — | US | disclosed |
| EP-1189893-A2 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONE | Bayer Aktiengesellschaft (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075119-A2 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |
| WO-2000043375-A2 | SUBSTITUTED ARYL HETEROCYCLIC COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069140-A1 | Substitutes 2-aryl-1,2,4-triazine-3,5-di(thi)one | DDT, SULT1E1, CYP1A1 | MEN1 3213/4885KMT2A 1064/4885NR1I2 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.