Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174458 | 0.87 | SLC5A1 (0.40) | MAPTLMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL6172002 | 0.87 | LMNA (0.41) | RXFP1MAPTIGF1RLMNAALDH1A1 | |
| SCHEMBL6174640 | 0.85 | IGF1R (0.37) | RXFP1IGF1RLMNASMN1; SMN2MAPK1 | |
| SCHEMBL6175175 | 0.85 | IGF1R (0.36) | IGF1RLMNASMN1; SMN2MAPK1 | |
| SCHEMBL6170251 | 0.84 | IGF1R (0.33) | IGF1RLMNA | |
| SCHEMBL6175260 | 0.84 | IGF1R (0.39) | IGF1RLMNASMN1; SMN2MAPK1 | |
| SCHEMBL6173330 | 0.83 | IGF1R (0.40) | IGF1RNR1H2NR1H3LMNASMN1; SMN2 | |
| SCHEMBL6171408 | 0.81 | IGF1R (0.35) | IGF1RLMNASMN1; SMN2MAPK1 | |
| SCHEMBL6175558 | 0.80 | RXFP1 (0.35) | RXFP1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6172647 | 0.80 | CYP3A4 (0.35) | RXFP1MAPTIGF1RNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |