Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174262 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL13114798 | 0.76 | MAPT (0.48) | ALDH1A1MAPTHTTKDM4EDRD2 | |
| SCHEMBL6174267 | 0.75 | GPR119 (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL5906035 | 0.74 | HCAR1 (0.50) | ALDH1A1MAPTSMN1; SMN2HTTKDM4E | |
| SCHEMBL7887520 | 0.74 | DRD4 (0.60) | ALDH1A1MAPTKDM4EDRD2DRD4 | |
| SCHEMBL3518937 | 0.70 | HTT (0.62) | ALDH1A1LMNASMN1; SMN2HTTKDM4E | |
| SCHEMBL29945199 | 0.69 | GAA (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL14884466 | 0.69 | GPR119 (0.48) | LMNAMAPTHTTDRD2DRD4 | |
| SCHEMBL20639686 | 0.69 | GPR119 (0.48) | MAPTHTT | |
| SCHEMBL3034991 | 0.69 | GPR119 (0.45) | ALDH1A1LMNAMAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497298-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087106-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-23 | — | — | WO | disclosed |