Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6174267 | 0.84 | GPR119 (0.48) | ALDH1A1ADRB1GPR119HTTLMNA | |
| SCHEMBL5906035 | 0.80 | HCAR1 (0.50) | ALDH1A1ADRB1HTTKDM4ERAB9A | |
| SCHEMBL6175083 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HTTLMNAKDM4EMAPT | |
| SCHEMBL7887520 | 0.80 | DRD4 (0.60) | ALDH1A1KDM4EMAPTSIGMAR1 | |
| SCHEMBL14884466 | 0.78 | GPR119 (0.48) | ADRB1GPR119HTTLMNAAKR1C3 | |
| SCHEMBL20639686 | 0.78 | GPR119 (0.48) | GPR119HTTAKR1C3ADRA1DADRA1A | |
| SCHEMBL3034991 | 0.74 | GPR119 (0.45) | ALDH1A1GPR119HTTLMNAAKR1C3 | |
| SCHEMBL3117217 | 0.74 | MAPT (0.52) | ALDH1A1ADRB1LMNARAB9AAKR1C3 | |
| SCHEMBL8718822 | 0.73 | HTT (0.50) | ALDH1A1GPR119HTTKDM4ERAB9A | |
| SCHEMBL19212308 | 0.73 | ADRB1 (0.59) | ALDH1A1ADRB1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261330-A1 | Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents | RANBAXY LABORATORIES LIMITED (IN) | 2005-11-24 | — | — | US | disclosed |
| EP-1497298-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087106-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261330-A1 | Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents | ERG28, DPM1, CYP51A1 | ALDH1A1 1062/4885ADRB1 4487/4885GPR119 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.