Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17679287 | 0.80 | GABRA1 (0.48) | GABRA1GABRB2HPGDSMN1; SMN2NOS3 | |
| SCHEMBL6176166 | 0.79 | HPGD (0.31) | HPGDSMN1; SMN2PDE3BPDE3ATRIM24 | |
| SCHEMBL18066852 | 0.78 | NOS2 (0.47) | GABRA1GABRB2HPGDSMN1; SMN2NOS3 | |
| SCHEMBL31299228 | 0.77 | KDM4E (0.41) | HPGDSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL845797 | 0.77 | HTT (0.37) | HPGDSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL7259584 | 0.77 | LIPG (0.40) | HPGDSMN1; SMN2 | |
| SCHEMBL24344266 | 0.75 | HPGD (0.46) | GABRA1GABRB2HPGDSMN1; SMN2 | |
| SCHEMBL7259052 | 0.75 | KDM4E (0.40) | GABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL27574983 | 0.74 | CA12 (0.39) | GABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL8775296 | 0.74 | KDM4E (0.43) | GABRA1GABRB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427719-B1 | 4-ALKYL-SUBSTITUTE THIENYLOXY-PYRIDINES | BASF AG (DE) | 2005-11-02 | — | — | EP | disclosed |
| EP-1427719-A1 | 4-ALKYL-SUBSTITUTE THIENYLOXY-PYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003022831-A1 | 4-ALKYL-SUBSTITUTE THIENYLOXY-PYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | WO | disclosed |