Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713334 | 0.91 | SIGMAR1 (0.53) | SIGMAR1RORCCNR2MAPTADRA2A | |
| SCHEMBL6189826 | 0.85 | PLK1 (0.41) | FEN1SLC6A4RORCCNR2 | |
| SCHEMBL6190194 | 0.85 | DRD2 (0.44) | SIGMAR1FEN1SLC6A4RORCCNR2 | |
| SCHEMBL6187775 | 0.85 | CNR2 (0.40) | SIGMAR1FEN1RORCCNR2ADRA2A | |
| SCHEMBL6191699 | 0.81 | L3MBTL1 (0.50) | — | |
| SCHEMBL6192479 | 0.81 | SIGMAR1 (0.45) | SIGMAR1FEN1RORCCNR2MAPT | |
| SCHEMBL6189813 | 0.81 | CDYL2 (0.47) | FEN1RORC | |
| SCHEMBL6187161 | 0.77 | TMEM97 (0.52) | SIGMAR1DRD2 | |
| SCHEMBL2593039 | 0.75 | SIGMAR1 (0.49) | SIGMAR1CNR2MAPTADRA2AADRA2B | |
| SCHEMBL7712492 | 0.75 | FPR2 (0.49) | SIGMAR1FEN1RORCFPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |