Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6189841 | 0.85 | PARP10 (0.36) | CNR2RAB9ANPC1PARP10FEN1 | |
| SCHEMBL6186909 | 0.85 | SIGMAR1 (0.48) | CNR2RORCFEN1ADRA2AADRA2B | |
| SCHEMBL6189826 | 0.85 | PLK1 (0.41) | CNR2RORCFEN1 | |
| SCHEMBL6190194 | 0.85 | DRD2 (0.44) | CNR2RORCRAB9ANPC1FEN1 | |
| SCHEMBL6191699 | 0.81 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL6186356 | 0.81 | P2RX3 (0.44) | CNR2RAB9ANPC1FEN1ATM | |
| SCHEMBL6189813 | 0.81 | CDYL2 (0.47) | RORCRAB9AFEN1KMT2A | |
| SCHEMBL6187161 | 0.77 | TMEM97 (0.52) | RAB9ANPC1SIGMAR1CYP2D6 | |
| SCHEMBL2590959 | 0.75 | KDM4E (0.40) | MEN1KMT2A | |
| SCHEMBL7713334 | 0.74 | SIGMAR1 (0.53) | CNR2RORCSMN1; SMN2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |