Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028848 | 0.86 | MAPT (0.61) | CYP1A2ALDH1A1LMNAALOX15MAPT | |
| SCHEMBL6794552 | 0.84 | PKM (0.55) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL6794355 | 0.83 | CYP1A2 (0.51) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL10750851 | 0.83 | CYP1A2 (0.51) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL6191755 | 0.83 | PGK1 (0.54) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL29736848 | 0.82 | CYP1A2 (0.60) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| Hydrochloric Acid SCHEMBL4849352 | 0.82 | RAB9A (0.54) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL10752732 | 0.81 | NPC1 (0.64) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL6792582 | 0.81 | PKM (0.47) | CYP1A2HRH3ALDH1A1LMNATAAR1 | |
| SCHEMBL6798950 | 0.80 | RAB9A (0.50) | CYP1A2HRH3ALDH1A1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589012-A2 | N-alkylheteroaryl secondary para-phenyldiamine, dyeing composition containing the same, process for making it and uses thereof | L'OREAL (FR) | 2005-10-26 | — | — | EP | claimed |
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | disclosed |
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | disclosed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| EP-1589012-A2 | N-alkylheteroaryl secondary para-phenyldiamine, dyeing composition containing the same, process for making it and uses thereof | L'OREAL (FR) | 2005-10-26 | — | — | EP | disclosed |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | KRT18, CDC73, PRKDC | CYP1A2 1286/4885HRH3 163/4885ALDH1A1 575/4885 |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | CYP1A2 640/4885HRH3 2617/4885ALDH1A1 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.