Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27583330 | 0.88 | PKM (0.47) | PKMCYP1A2LMNATDP1MAPK1 | |
| SCHEMBL6792690 | 0.81 | ALDH1A1 (0.65) | PKMCYP1A2LMNATDP1MAPK1 | |
| SCHEMBL6187553 | 0.81 | CYP1A2 (0.51) | PKMCYP1A2LMNATDP1HRH3 | |
| SCHEMBL6794552 | 0.79 | PKM (0.55) | PKMCYP1A2LMNATDP1HRH3 | |
| SCHEMBL6794355 | 0.78 | CYP1A2 (0.51) | PKMCYP1A2LMNAHRH3ALDH1A1 | |
| SCHEMBL6191755 | 0.78 | PGK1 (0.54) | PKMCYP1A2LMNAHRH3ALDH1A1 | |
| SCHEMBL10836345 | 0.77 | CYP1A2 (0.53) | PKMCYP1A2LMNATDP1MAPK1 | |
| Hydrochloric Acid SCHEMBL4849352 | 0.77 | RAB9A (0.54) | PKMCYP1A2LMNAHRH3ALDH1A1 | |
| SCHEMBL17774852 | 0.74 | THRA (0.56) | LMNAALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3993461 | 0.71 | CYP1A2 (0.60) | PKMCYP1A2LMNATDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | PKM 3447/4885CYP1A2 640/4885LMNA 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.