Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3695195 | 0.83 | OPRM1 (0.76) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL6187612 | 0.76 | LPAR1 (0.49) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.76 | LMNA (0.73) | MAPTL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL13535161 | 0.75 | L3MBTL1 (0.63) | MAPTL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL8737718 | 0.74 | NPC1 (0.72) | MAPTL3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL2851561 | 0.73 | LMNA (0.61) | MAPTL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL160715 | 0.73 | LMNA (0.61) | MAPTL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL6554125 | 0.73 | LMNA (0.65) | MAPTL3MBTL1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL23291312 | 0.72 | MAPT (0.66) | MAPTL3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL10447512 | 0.72 | L3MBTL1 (0.59) | MAPTL3MBTL1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562595-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004026305-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | ELI LILLY AND COMPANY (US) | 2004-04-01 | — | — | WO | disclosed |