Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 5/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 2/20 | 0.37 |
| ▸ | SCN4A | P35499 | 3/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621084 | 0.92 | TLR8 (0.42) | TP53HSD17B10KMT2AMEN1DCPS | |
| SCHEMBL620979 | 0.91 | TP53 (0.40) | TP53HSD17B10KMT2AMEN1DCPS | |
| SCHEMBL15677270 | 0.89 | TLR8 (0.46) | TP53HSD17B10KMT2AMEN1DCPS | |
| SCHEMBL28073770 | 0.89 | TP53 (0.40) | TP53HSD17B10KMT2AMEN1DCPS | |
| SCHEMBL621331 | 0.89 | TP53 (0.40) | TP53HSD17B10KMT2AMEN1DCPS | |
| SCHEMBL28451675 | 0.88 | GABRP (0.46) | TP53HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL28449459 | 0.88 | GABRP (0.46) | TP53HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL28449457 | 0.88 | GABRP (0.46) | TP53HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL619413 | 0.87 | TP53 (0.43) | TP53HSD17B10KMT2AMEN1DCPS | |
| SCHEMBL27102660 | 0.83 | RAB9A (0.40) | TP53HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
| CN-102933081-B | Sweet flavor modifier | SENOMYX, INC. (US) | 2016-04-13 | — | — | CN | disclosed |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2015-09-24 | — | — | US | disclosed |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2015-09-03 | — | — | US | disclosed |
| US-9049878-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-9000054-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| EP-2552207-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011123693-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | TP53 2058/4885HSD17B10 3150/4885KMT2A 740/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | TP53 2058/4885HSD17B10 3150/4885KMT2A 740/4885 |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | TP53 2058/4885HSD17B10 3150/4885KMT2A 740/4885 |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | TP53 2533/4885HSD17B10 1094/4885KMT2A 1673/4885 |
| US-20150265711-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | TP53 2533/4885HSD17B10 1094/4885KMT2A 1673/4885 |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | TP53 2533/4885HSD17B10 1094/4885KMT2A 1673/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | TP53 2058/4885HSD17B10 3150/4885KMT2A 740/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | TP53 2058/4885HSD17B10 3150/4885KMT2A 740/4885 |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | TP53 2533/4885HSD17B10 1094/4885KMT2A 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.