SCHEMBL618906

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL616544	0.93	NISCH (0.36)	CHEK1NISCHNPC1RAB9AS1PR1
	SCHEMBL618061	0.90	KMT2A (0.38)	CHEK1MAPK1LMNAUSP2FYN
	SCHEMBL619308	0.82	CYP2D6 (0.43)	CYP19A1LMNANPC1RAB9AMAPT
	SCHEMBL615696	0.82	MGAM (0.46)	MAPK1LMNANPC1RAB9AMAPT
	SCHEMBL618252	0.82	LMNA (0.39)	MAPK1LMNAUSP2NPC1RAB9A
	SCHEMBL615767	0.82	CYP1A1 (0.45)	LMNANPC1RAB9AALDH1A1POLB
	SCHEMBL616540	0.82	TUBB4A (0.40)	GABRA1GABRB2ALOX5CYP19A1MAPT
	SCHEMBL618793	0.82	ALDH1A1 (0.43)	LMNANPC1MAPTALDH1A1POLB
	SCHEMBL618801	0.81	PDE10A (0.43)	ALOX5MAPK1LMNAUSP2S1PR1
	SCHEMBL618114	0.81	CYP1A1 (0.43)	MAPK1LMNAUSP2FYNS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.