SCHEMBL61896

SCHEMBL61896

CCOC(C)OC(=O)/C=C/c1ccccc1OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.57
HPGD P15428 7/20 0.57
ALDH1A1 P00352 6/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
NFE2L2 Q16236 2/20 0.57
TFEB P19484 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.53
MAPT P10636 4/20 0.51
LMNA P02545 3/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 2/20 0.51
BCHE P06276 1/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
ALOX12 P18054 1/20 0.51
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LY96 Q9Y6Y9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19244449 0.84 KDM4E (0.63) KDM4EHPGDALDH1A1L3MBTL1NFE2L2
SCHEMBL19244450 0.84 KDM4E (0.63) KDM4EHPGDALDH1A1L3MBTL1NFE2L2
SCHEMBL19244299 0.83 NFE2L2 (0.66) KDM4EHPGDALDH1A1L3MBTL1NFE2L2
SCHEMBL15836 0.83 NFE2L2 (0.66) KDM4EHPGDALDH1A1L3MBTL1NFE2L2
Propionic Acid SCHEMBL28155113 0.82 NFE2L2 (0.57) KDM4EHPGDALDH1A1L3MBTL1NFE2L2
SCHEMBL15188 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NFE2L2TFEB
SCHEMBL4775241 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NFE2L2TFEB
SCHEMBL31506312 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NFE2L2TFEB
SCHEMBL13957562 0.80 KDM4E (0.67) KDM4EHPGDALDH1A1NFE2L2TFEB
SCHEMBL31419776 0.80 SMN1; SMN2 (0.54) KDM4EHPGDALDH1A1L3MBTL1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10555892-B1 Functionalized siloxane or polysiloxane coated particles with enhanced light filtering properties NANOPHASE TECHNOLOGIES CORPORATION (US) 2020-02-11 US claimed
US-20150174045-A1 LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER DSM IP ASSETS B.V. (NL) 2015-06-25 US claimed
WO-2013102248-A2 \"AQUEOUS COSMETIC SUNSCREEN COMPOSITION AND USE THEREOF, COSMETIC METHOD FOR APPLICATION OF SAID COMPOSITION, COSMETIC METHOD TO PREVENT AND CONTROL SKIN OILINESS, COSMETIC METHOD TO PROTECT THE SKIN FROM THE DAMAGES CAUSED BY ULTRAVIOLET RADIATION, AND COSMETIC PRODUCT.\ . JOHNSON & JOHNSON DO BRASIL INDUSTRIA E COMERCIO DE PRODUTOS PARA SAUDE LTDA. (BR) 2013-07-11 WO claimed
EP-1899015-B1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSM IP ASSETS BV (NL) 2012-03-21 EP claimed
WO-2009129855-A1 PHOTOPROTECTIVE COMPOSITIONS CONTAINING PEPTIDES UNITED TECHNOLOGIES UT AG (CH) 2009-10-29 WO claimed
US-20080199526-A1 Composition With Tight Capsules Containing a Sunscreen Agent DSM IP ASSETS B.V. (NL) 2008-08-21 US claimed
EP-1899015-A1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSMIP Assets B.V. (NL) 2008-03-19 EP claimed
WO-2007000316-A1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSM IP ASSETS B.V. (NL) 2007-01-04 WO claimed
WO-2026087156-A1 PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2026-04-30 WO disclosed
US-12582587-B2 Sunscreen composition and methods of protection from ultraviolet and visible light DOC MARTIN'S OF MAUI (US) 2026-03-24 US disclosed
EP-4665297-A1 A COSMETIC COMPOSITION Unilever IP Holdings B.V. (NL) 2025-12-24 EP disclosed
US-12409115-B2 Sunscreen composition comprising visible light protecting agents and methods of use DOC MARTIN'S OF MAUI (US) 2025-09-09 US disclosed
EP-3471694-B1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS KENVUE BRANDS LLC (US) 2025-07-02 EP disclosed
CN-120201986-A Sun-proof cosmetic 株式会社高丝 2025-06-24 CN disclosed
EP-0998906-A2 Shampoo composition F. HOFFMANN-LA ROCHE AG (CH) 2000-05-10 EP disclosed
EP-0979645-A1 Light screening composition containing a polysiloxane type UV-B screening agent and a benzimidazol type UV-B screening agent F. HOFFMANN-LA ROCHE AG (CH) 2000-02-16 EP disclosed
US-6018044-A TRIS((ALKYL, SILANE, OLIGOSILOXANE OR POLYSILOXANE)(OXY OR AMINO)CARBONYL-(1,4-PHENYLENE)-AMINO)-S-TRIAZINES HAVING AT LEAST ONE SILICON CONTAINING MOIETY OF GIVEN FORMULA; USE AS UV-B FILTERS IN LIGHT SCREENING COMPOSITIONS ROCHE VITAMINS INC. (US) 2000-01-25 US disclosed
US-5985251-A DIBENZOYLMETHANE DERIVATIVE, 3,3-DIPHENYLACRYLATE- OR BENZYLIDENE CAMPHOR DERIVATIVE, P-METHOXYCINNAMATE DERIVATIVE, ROCHE VITAMINS INC. (US) 1999-11-16 US disclosed
EP-0933376-A2 Silanyl-triazines as light screening compositions F. HOFFMANN-LA ROCHE AG (CH) 1999-08-04 EP disclosed
EP-0920858-A2 Light screening composition F. HOFFMANN-LA ROCHE AG (CH) 1999-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10555892-B1 Functionalized siloxane or polysiloxane coated particles with enhanced light filtering properties SPIN4, RPS4X, RPS4Y1 KDM4E 1042/4885HPGD 4771/4885ALDH1A1 3150/4885
US-12582587-B2 Sunscreen composition and methods of protection from ultraviolet and visible light SOD1, TYR, SLC40A1 KDM4E 3241/4885HPGD 1381/4885ALDH1A1 645/4885
US-20080199526-A1 Composition With Tight Capsules Containing a Sunscreen Agent SUN2, DSG1, DSC1 KDM4E 604/4885HPGD 808/4885ALDH1A1 258/4885
US-20150174045-A1 LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER ERCC4, ERCC2, ERCC1 KDM4E 2251/4885HPGD 1636/4885ALDH1A1 2214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.