Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HAT1 | O14929 | 11/20 | 0.44 |
| ▸ | EP300 | Q09472 | 11/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10525622 | 0.98 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1L3MBTL1CES2 | |
| SCHEMBL10523603 | 0.85 | L3MBTL1 (0.51) | ALDH1A1KDM4ETDP1L3MBTL1LMNA | |
| SCHEMBL6275504 | 0.85 | HAT1 (0.54) | ALDH1A1CES2LMNACES1HAT1 | |
| SCHEMBL6202507 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1KDM4ETDP1L3MBTL1CES2 | |
| SCHEMBL28513139 | 0.84 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6321040 | 0.83 | HAT1 (0.54) | HAT1EP300 | |
| SCHEMBL6203337 | 0.81 | TDP1 (0.50) | ALDH1A1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL6202101 | 0.79 | MEP1B (0.57) | TDP1L3MBTL1CES2LMNACES1 | |
| Hydrochloric Acid SCHEMBL10526098 | 0.79 | MDM2 (0.48) | ALDH1A1KDM4ELMNAHAT1EP300 | |
| SCHEMBL6202712 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1KDM4ETDP1L3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |