Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806205 | 0.93 | HTT (0.56) | HTTCTSLFOLH1CTRB1CASP1 | |
| SCHEMBL7976786 | 0.86 | CTRB1 (0.50) | HTTCTSLCTRB1SLC1A3SLC1A1 | |
| SCHEMBL5501379 | 0.86 | CTSL (0.61) | CTSLCTRB1ATM | |
| SCHEMBL4368421 | 0.85 | CTSL (0.57) | CTSL | |
| SCHEMBL5711264 | 0.83 | FOLH1 (0.67) | HTTCTSLFOLH1SIRT5CASP1 | |
| SCHEMBL6278137 | 0.83 | FOLH1 (0.67) | HTTCTSLFOLH1SIRT5CASP1 | |
| SCHEMBL5711173 | 0.83 | FOLH1 (0.67) | HTTCTSLFOLH1SIRT5CASP1 | |
| SCHEMBL6941323 | 0.82 | CASP1 (0.56) | HTTCTRB1CASP1ATMCA12 | |
| SCHEMBL6200622 | 0.82 | CASP1 (0.56) | HTTCTRB1CASP1ATMCA12 | |
| SCHEMBL6937929 | 0.82 | CASP1 (0.56) | HTTCTRB1CASP1ATMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |