Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | KLK8 | O60259 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202368 | 0.86 | HTT (0.59) | CTRB1CTSLSLC1A3SLC1A1ATM | |
| SCHEMBL5501379 | 0.86 | CTSL (0.61) | CTRB1CTSLATMCTSSCTSK | |
| SCHEMBL4368421 | 0.85 | CTSL (0.57) | CTSLCTSSCTSK | |
| SCHEMBL6806205 | 0.84 | HTT (0.56) | CTRB1CTSLSLC1A3SLC1A1ATM | |
| Hydrochloric Acid SCHEMBL10636143 | 0.82 | CTSK (0.55) | CTRB1CTSLATMCTSSTRPM8 | |
| SCHEMBL10953605 | 0.81 | CTRB1 (0.64) | CTRB1CTSLF2PLAUPLAT | |
| SCHEMBL14625712 | 0.81 | CTRB1 (0.64) | CTRB1CTSLF2PLAUPLAT | |
| SCHEMBL14675316 | 0.80 | IDO1 (0.46) | SLC1A3SLC1A1 | |
| SCHEMBL6941323 | 0.80 | CASP1 (0.56) | CTRB1ATMCA12CA1CA2 | |
| SCHEMBL6200622 | 0.80 | CASP1 (0.56) | CTRB1ATMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |