Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207381 | 0.87 | MARS1 (0.33) | CACNA1BPTGS2 | |
| SCHEMBL6175775 | 0.84 | PTGS2 (0.33) | PTGS1PTGS2 | |
| SCHEMBL2939721 | 0.75 | ENPP2 (0.38) | CACNA1BPTGS1PTGS2BCL2L1 | |
| SCHEMBL6173288 | 0.71 | MAPT (0.32) | — | |
| SCHEMBL6171783 | 0.71 | CACNA1B (0.35) | CACNA1BPTGS1PTGS2 | |
| SCHEMBL6174915 | 0.71 | MAPT (0.38) | CACNA1B | |
| SCHEMBL2941888 | 0.67 | IGF1R (0.38) | CACNA1BPTGS1PTGS2 | |
| SCHEMBL6173810 | 0.67 | MAPT (0.35) | PTGS2 | |
| SCHEMBL2942214 | 0.67 | IGF1R (0.47) | CACNA1BBCL2L1 | |
| SCHEMBL2939355 | 0.66 | ENPP2 (0.43) | CACNA1BPTGS1PTGS2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |