Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201652 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1TSHRNPC1TP53 | |
| SCHEMBL6203370 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1TSHRNPC1 | |
| SCHEMBL20139663 | 0.73 | ROCK2 (0.39) | ALDH1A1HDAC4FEN1 | |
| SCHEMBL20139640 | 0.67 | GAA (0.46) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL20139617 | 0.65 | HDAC4 (0.41) | HDAC4FEN1 | |
| SCHEMBL14073806 | 0.64 | ALDH1A1 (0.56) | MAPTALDH1A1TSHRTP53POLB | |
| SCHEMBL7902879 | 0.64 | KMT2A (0.56) | SMN1; SMN2MAPTALDH1A1TSHRNPC1 | |
| SCHEMBL6201649 | 0.64 | ALDH1A1 (0.43) | SMN1; SMN2MAPTALDH1A1TSHRNPC1 | |
| SCHEMBL15988741 | 0.63 | CTNNB1 (0.52) | SMN1; SMN2MAPTALDH1A1TSHRNPC1 | |
| SCHEMBL7932102 | 0.63 | ALDH1A1 (0.63) | SMN1; SMN2MAPTALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |