Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201493 | 0.80 | LMNA (0.46) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL6203371 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1POLBL3MBTL1MAPK1MAPT | |
| SCHEMBL6202065 | 0.77 | POLB (0.42) | POLBKMT2ANPC1TP53RAB9A | |
| SCHEMBL6201649 | 0.76 | ALDH1A1 (0.43) | ALDH1A1POLBHPGDHSD17B10ALOX15 | |
| SCHEMBL6075034 | 0.66 | HSD17B10 (0.63) | ALDH1A1POLBHPGDHSD17B10ALOX15 | |
| SCHEMBL7363506 | 0.66 | TBXAS1 (0.49) | HPGDHTTLMNA | |
| SCHEMBL28804493 | 0.66 | LMNA (0.41) | L3MBTL1MEN1KMT2ATSHRLMNA | |
| SCHEMBL6075198 | 0.65 | POLB (0.51) | ALDH1A1POLBHPGDHSD17B10ALOX15 | |
| SCHEMBL6201073 | 0.65 | CYP19A1 (0.53) | ALDH1A1POLBHPGDMEN1HTT | |
| SCHEMBL14073806 | 0.65 | ALDH1A1 (0.56) | ALDH1A1POLBHPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |