Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204707 | 0.84 | MGAM (0.49) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6202787 | 0.84 | MGAM (0.52) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6203751 | 0.75 | MAPK1 (0.46) | GAAALDH1A1LMNAKDM4EPKM | |
| SCHEMBL9877764 | 0.70 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4EPKMSMN1; SMN2 | |
| SCHEMBL9877648 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4EPKMSMN1; SMN2 | |
| SCHEMBL838069 | 0.70 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EPKMSMN1; SMN2 | |
| SCHEMBL6202785 | 0.70 | NPC1 (0.46) | GAAALDH1A1LMNAKDM4EPKM | |
| SCHEMBL11096738 | 0.69 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4EPKMSMN1; SMN2 | |
| SCHEMBL10685497 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNAKDM4EPKMSMN1; SMN2 | |
| SCHEMBL9878025 | 0.68 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4EPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |