Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27427349 | 0.76 | LTA4H (0.35) | — | |
| SCHEMBL6204590 | 0.74 | LDHA (0.33) | — | |
| SCHEMBL251489 | 0.73 | HPGD (0.34) | — | |
| SCHEMBL27427352 | 0.67 | CA2 (0.46) | — | |
| SCHEMBL2585956 | 0.66 | CALM1 (0.43) | — | |
| SCHEMBL1166414 | 0.65 | HPGD (0.33) | — | |
| SCHEMBL27545293 | 0.65 | IDO1 (0.39) | — | |
| SCHEMBL3031682 | 0.64 | TAAR1 (0.36) | — | |
| SCHEMBL27456639 | 0.64 | LTA4H (0.33) | — | |
| SCHEMBL14740719 | 0.63 | PNMT (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |