Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 10/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628858 | 1.00 | MAPK1 (0.42) | MAPK1SMN1; SMN2SSTR4CASRSSTR1 | |
| SCHEMBL620633 | 0.87 | SSTR4 (0.43) | SSTR4SSTR1 | |
| SCHEMBL12219488 | 0.84 | SSTR4 (0.40) | SMN1; SMN2SSTR4CASRSSTR1ADRB2 | |
| SCHEMBL617883 | 0.83 | SSTR4 (0.40) | SSTR4SSTR1 | |
| SCHEMBL617944 | 0.83 | CYP2C9 (0.48) | SMN1; SMN2SSTR4DGAT1LMNA | |
| SCHEMBL618829 | 0.82 | SSTR4 (0.56) | SSTR4SSTR1 | |
| SCHEMBL620805 | 0.81 | LMNA (0.40) | MAPK1SMN1; SMN2SSTR4CYP2D6KCNH2 | |
| SCHEMBL618382 | 0.81 | SSTR4 (0.39) | SMN1; SMN2SSTR4SSTR1LMNA | |
| SCHEMBL13476078 | 0.81 | SSTR4 (0.37) | SMN1; SMN2SSTR4CASRLMNA | |
| SCHEMBL13476063 | 0.81 | SSTR4 (0.37) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250223261-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | FIRMENICH SA (CH) | 2025-07-10 | — | — | US | disclosed |
| EP-4472950-B1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | FIRMENICH & CIE (CH) | 2025-06-25 | — | — | EP | disclosed |
| EP-4472950-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | Firmenich SA (CH) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023209143-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | FIRMENICH SA (CH) | 2023-11-02 | — | — | WO | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-9834544-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2015-09-03 | — | — | US | disclosed |
| US-20150141527-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2015-05-21 | — | — | US | disclosed |
| US-9000054-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| US-8815956-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| EP-2742026-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2014-06-18 | — | — | EP | disclosed |
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2013025560-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2013-02-21 | — | — | WO | disclosed |
| US-20130041046-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | MAPK1 4218/4885SMN1; SMN2 101/4885SSTR4 2147/4885 |
| US-20250223261-A1 | PROCESS FOR MAKING A TASTE-MODIFYING COMPOUND | TAS2R4, TAS2R50, TAS2R60 | MAPK1 1603/4885SMN1; SMN2 1455/4885SSTR4 419/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | MAPK1 4218/4885SMN1; SMN2 101/4885SSTR4 2147/4885 |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | MAPK1 4218/4885SMN1; SMN2 101/4885SSTR4 2147/4885 |
| US-20130041046-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | MAPK1 4386/4885SMN1; SMN2 3028/4885SSTR4 764/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | MAPK1 4218/4885SMN1; SMN2 101/4885SSTR4 2147/4885 |
| US-20150141527-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | MAPK1 4386/4885SMN1; SMN2 3028/4885SSTR4 764/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | MAPK1 4218/4885SMN1; SMN2 101/4885SSTR4 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.