Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 15/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | RPS27 | P42677 | 1/20 | 0.34 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618382 | 0.93 | SSTR4 (0.39) | SSTR4SSTR1KDM4EMAPK8MAPK9 | |
| SCHEMBL620805 | 0.89 | LMNA (0.40) | SSTR4KDM4EMAPK8MAPK9MAPK10 | |
| SCHEMBL12218973 | 0.86 | ADRB1 (0.44) | SSTR4SSTR1 | |
| SCHEMBL620633 | 0.86 | SSTR4 (0.43) | SSTR4SSTR1MAPK8MAPK9 | |
| SCHEMBL619134 | 0.84 | SMN1; SMN2 (0.39) | SSTR4KDM4EMAPK8MAPK9MAPK10 | |
| SCHEMBL12219488 | 0.83 | SSTR4 (0.40) | SSTR4SSTR1KDM4EMAPK8MAPK9 | |
| SCHEMBL620997 | 0.83 | SSTR4 (0.37) | SSTR4SSTR1KDM4EMAPK8MAPK9 | |
| SCHEMBL620597 | 0.83 | MAPK1 (0.42) | SSTR4SSTR1 | |
| SCHEMBL30628858 | 0.83 | MAPK1 (0.42) | SSTR4SSTR1 | |
| SCHEMBL621268 | 0.83 | KMT2A (0.43) | SSTR4SSTR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-107365319-B | Modulation of chemosensory receptors and ligands associated therewith | 弗门尼舍公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| US-10570105-B2 | Processes and intermediates for making sweet taste enhancers | FIRMENICH INCORPORATED (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190263762-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | FIRMENICH INCORPORATED | 2019-08-29 | — | — | US | disclosed |
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10308621-B2 | Processes and intermediates for making sweet taste enhancers | SENOMYX, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| EP-2552207-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011123693-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110245494-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010014666-A2 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | SENOMYX, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| EP-2062050-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | Senomyx, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008154221-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | SSTR4 2147/4885SSTR1 2142/4885KDM4E 476/4885 |
| US-10308621-B2 | Processes and intermediates for making sweet taste enhancers | TAS2R40, TAS2R4, TAS2R45 | SSTR4 450/4885SSTR1 815/4885KDM4E 1115/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | SSTR4 2147/4885SSTR1 2142/4885KDM4E 476/4885 |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SSTR4 156/4885SSTR1 192/4885KDM4E 1475/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | SSTR4 2147/4885SSTR1 2142/4885KDM4E 476/4885 |
| US-10570105-B2 | Processes and intermediates for making sweet taste enhancers | TAS2R13, TAS2R10, TAS2R20 | SSTR4 86/4885SSTR1 46/4885KDM4E 1780/4885 |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | TAS2R30, TAS2R50, TAS2R1 | SSTR4 263/4885SSTR1 180/4885KDM4E 4555/4885 |
| US-20110245494-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R50, TAS2R30, TAS2R10 | SSTR4 131/4885SSTR1 111/4885KDM4E 1001/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | SSTR4 2147/4885SSTR1 2142/4885KDM4E 476/4885 |
| US-20190263762-A1 | PROCESSES AND INTERMEDIATES FOR MAKING SWEET TASTE ENHANCERS | TAS2R13, TAS2R10, TAS2R20 | SSTR4 86/4885SSTR1 46/4885KDM4E 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.