Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220305 | 0.86 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPK1TDP1KMT2A | |
| SCHEMBL5831442 | 0.84 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPK1TDP1KMT2A | |
| SCHEMBL11323383 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2AMEN1NPC1 | |
| SCHEMBL28297471 | 0.81 | POLB (0.52) | ALDH1A1HPGDMAPK1TDP1KMT2A | |
| SCHEMBL1447712 | 0.80 | MDM4 (0.46) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL1447993 | 0.80 | L3MBTL1 (0.46) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7399776 | 0.79 | HDAC1 (0.46) | ALDH1A1HPGDMAPK1KMT2AMEN1 | |
| SCHEMBL10803626 | 0.79 | NPC1 (0.43) | ALDH1A1HPGDNPC1RAB9APOLB | |
| SCHEMBL21357 | 0.79 | CA1 (0.45) | ALDH1A1HPGDKMT2AMEN1NPC1 | |
| SCHEMBL6197771 | 0.78 | HSD17B10 (0.51) | ALDH1A1HPGDKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748780-A | The synthetic method of a kind of four poly- benzyl compounds | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | claimed |
| US-20050288336-A1 | Cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | claimed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | claimed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | claimed |
| WO-1999011633-A1 | TRIAZINES WITH AN ADENOSINE ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-03-11 | — | — | WO | claimed |
| US-4262851-A | HIGH SPEED MILLING WITHOUT SURFACTANTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | claimed |
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |
| CN-109748780-A | The synthetic method of a kind of four poly- benzyl compounds | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |
| US-20050288336-A1 | Cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | disclosed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
| WO-1999011633-A1 | TRIAZINES WITH AN ADENOSINE ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-03-11 | — | — | WO | disclosed |
| US-4262851-A | HIGH SPEED MILLING WITHOUT SURFACTANTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288336-A1 | Cysteine protease inhibitors | CTSF, CTSS, CTSB | ALDH1A1 2872/4885HPGD 1670/4885ESR1 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.