SCHEMBL620668

SCHEMBL620668

COC(=O)c1cc2ccccc2cc1OC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
HPGD P15428 4/20 0.71
KDM4E B2RXH2 4/20 0.71
KMT2A Q03164 5/20 0.60
NPC1 O15118 5/20 0.60
MEN1 O00255 4/20 0.60
POLB P06746 4/20 0.59
RAB9A P51151 4/20 0.59
AHR P35869 2/20 0.59
CASP3 P42574 1/20 0.57
ATM Q13315 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
MAPT P10636 1/20 0.54
TSHR P16473 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SLC6A2 P23975 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438041 0.86 KDM4E (0.61) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL68218 0.86 KDM4E (0.61) ALDH1A1HPGDKDM4EKMT2AMEN1
SCHEMBL20427593 0.86 ALDH1A1 (0.53) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL13955899 0.86 ALDH1A1 (0.67) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL3675717 0.84 NPC1 (0.70) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL31605176 0.83 ALDH1A1 (0.73) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL617928 0.83 ALDH1A1 (1.00) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL407744 0.83 ALDH1A1 (0.73) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL1127591 0.83 KDM4E (0.69) ALDH1A1HPGDKDM4EKMT2ANPC1
SCHEMBL9216610 0.83 KDM4E (0.74) ALDH1A1HPGDKDM4EKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
CN-118894823-A Naphthylamide compound serving as VEGFR inhibitor and application thereof 重庆医科大学 2024-11-05 CN disclosed
WO-2024024490-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM 日産化学株式会社 2024-02-01 WO disclosed
WO-2023238920-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM TO REDUCE ENVIRONMENTAL IMPACT 日産化学株式会社 2023-12-14 WO disclosed
US-20230381740-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2023-11-30 US disclosed
US-20230381740-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2023-11-30 US disclosed
WO-2023181960-A1 COMPOSITION FOR FORMING PROTECTIVE FILM 日産化学株式会社 2023-09-28 WO disclosed
US-11679372-B2 Multivariate metal-organic frameworks for fine-tuning light emission UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-06-20 US disclosed
US-11679372-B2 Multivariate metal-organic frameworks for fine-tuning light emission UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-06-20 US disclosed
US-11618722-B2 Compound, composition, organic electroluminescent element, and electronic appliance IDEMITSU KOSAN CO., LTD. (JP) 2023-04-04 US disclosed
WO-2000041698-A1 φ-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS BAYER CORPORATION (US) 2000-07-20 WO disclosed
WO-2000042012-A1 φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS BAYER CORPORATION (US) 2000-07-20 WO disclosed
US-6051712-A PREVENTION OF HIGH BLOOD PRESSURE AND CARDIAC INSUFFICIENCY, AS WELL AS GLAUCOMA, CARDIAC INFARCT, KIDNEY INSUFFICIENCY AND RESTENOSIS HOFFMANN-LA ROCHE INC. (US) 2000-04-18 US disclosed
WO-1999032436-A1 INHIBITION OF RAF KINASE USING SYMMETRICAL AND UNSYMMETRICAL SUBSTITUTED DIPHENYL UREAS BAYER CORPORATION (US) 1999-07-01 WO disclosed
WO-1999032463-A1 INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS BAYER CORPORATION (US) 1999-07-01 WO disclosed
US-5849781-A Tricyclic amides ADIR ET COMPAGNIE (FR) 1998-12-15 US disclosed
US-5712312-A MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS ADIR ET COMPAGNIE (FR) 1998-01-27 US disclosed
US-4432986-A N-(TETRAZOL-5-YL)-(DIBENZOTHIOPHENE-, OR DIBENZOFURAN-, OR 1,3-BEZODIOXOLE-, OR NAPHTHALENE-)-4-CARBOXAMIDE RIKER LABORATORIES, INC. (US) 1984-02-21 US disclosed
US-4123219-A PHOTOCHEMICAL DIMERIZATION OF TWO NAPHTHALENE COMPOUNDS AND HEATING PRODUCT TO RELEASE ENERGY AS HEAT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH (AU) 1978-10-31 US disclosed
US-3994675-A Chemical storage of radiant energy COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11679372-B2 Multivariate metal-organic frameworks for fine-tuning light emission ILF2, MORF4L1, YTHDF2 ALDH1A1 3245/4885HPGD 4666/4885KDM4E 1226/4885
US-20230381740-A1 MULTIVARIATE METAL-ORGANIC FRAMEWORKS FOR FINE-TUNING LIGHT EMISSION ILF2, MORF4L1, YTHDF2 ALDH1A1 3245/4885HPGD 4666/4885KDM4E 1226/4885
US-11618722-B2 Compound, composition, organic electroluminescent element, and electronic appliance FGF23, SUZ12, RPL24 ALDH1A1 3606/4885HPGD 3219/4885KDM4E 503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.