Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208765 | 0.79 | CTSL (0.36) | CTSLCTSBCTSS | |
| SCHEMBL4701834 | 0.77 | CTSB (0.39) | CTSLCTSBCTSS | |
| SCHEMBL6208510 | 0.77 | CTSB (0.39) | CTSLCTSBCTSS | |
| SCHEMBL4703744 | 0.75 | KDM4E (0.36) | CTSLCTSBCTSS | |
| SCHEMBL4703503 | 0.75 | KDM4E (0.36) | CTSLCTSBCTSS | |
| SCHEMBL4703890 | 0.72 | CTSS (0.40) | CTSLCTSBCTSS | |
| SCHEMBL4704327 | 0.72 | CTSL (0.51) | CTSLCTSBCTSS | |
| SCHEMBL4698962 | 0.72 | CTSL (0.37) | CTSLCTSBCTSS | |
| SCHEMBL4704891 | 0.71 | CTSL (0.37) | CTSLCTSBCTSS | |
| SCHEMBL4701851 | 0.71 | CTSL (0.49) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-A4 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2005-10-12 | — | — | EP | disclosed |
| EP-1372655-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada & Co. (CA) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002069901-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2002-09-12 | — | — | WO | disclosed |