Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211427 | 0.95 | ALDH1A1 (0.36) | CTSKCHRM1MEN1ALDH1A1KMT2A | |
| SCHEMBL6209110 | 0.94 | HSD17B10 (0.39) | CHRM1ALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL6212580 | 0.93 | ALDH1A1 (0.39) | CHRM1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6210187 | 0.92 | CTSK (0.40) | CTSKHDAC3HDAC8 | |
| SCHEMBL6212287 | 0.91 | CTSK (0.41) | CTSKHDAC3HDAC8 | |
| SCHEMBL6213622 | 0.91 | LMNA (0.38) | ALDH1A1KMT2ASMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL6212436 | 0.90 | LMNA (0.38) | ALDH1A1KMT2ALMNAHSD17B10 | |
| SCHEMBL6211558 | 0.90 | LMNA (0.38) | ALDH1A1KMT2ALMNAITGB3ITGA2B | |
| SCHEMBL6209295 | 0.90 | CTSK (0.37) | CTSKHDAC3HDAC8HTR1AHTR2A | |
| SCHEMBL6211355 | 0.90 | LMNA (0.36) | ALDH1A1KMT2ALMNAITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |