Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211427 | 0.94 | ALDH1A1 (0.36) | HSD17B10SMN1; SMN2TP53ALDH1A1LMNA | |
| SCHEMBL6208961 | 0.94 | CTSK (0.38) | HSD17B10SMN1; SMN2ALDH1A1LMNACHRM1 | |
| SCHEMBL6212580 | 0.93 | ALDH1A1 (0.39) | HSD17B10SMN1; SMN2ALDH1A1LMNASMYD3 | |
| SCHEMBL6213622 | 0.90 | LMNA (0.38) | HSD17B10TSHRSMN1; SMN2ALDH1A1NAMPT | |
| SCHEMBL6211651 | 0.90 | NAMPT (0.38) | HSD17B10TSHRSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL6211558 | 0.89 | LMNA (0.38) | HSD17B10TSHRALDH1A1LMNASMYD3 | |
| SCHEMBL6212436 | 0.89 | LMNA (0.38) | HSD17B10TSHRALDH1A1LMNASMYD3 | |
| SCHEMBL6213162 | 0.88 | CTSK (0.42) | HSD17B10TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6209651 | 0.88 | LMNA (0.42) | TP53NAMPTLMNA | |
| SCHEMBL6211403 | 0.88 | NAMPT (0.37) | HSD17B10NAMPTLMNASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |