Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213622 | 0.92 | LMNA (0.38) | NAMPTLMNADPP4HSD17B10ELOVL6 | |
| SCHEMBL6210134 | 0.92 | LMNA (0.43) | NAMPTCCR5LMNAHSD17B10ELOVL6 | |
| SCHEMBL6212436 | 0.91 | LMNA (0.38) | CCR5LMNAHSD17B10ELOVL6SMYD3 | |
| SCHEMBL6211558 | 0.91 | LMNA (0.38) | LMNAHSD17B10ELOVL6SMYD3 | |
| SCHEMBL6213162 | 0.90 | CTSK (0.42) | LMNAHSD17B10ELOVL6CTSKSMYD3 | |
| SCHEMBL6209651 | 0.90 | LMNA (0.42) | NAMPTLMNADPP4ELOVL6 | |
| SCHEMBL6211570 | 0.90 | SLC6A5 (0.38) | NAMPTCCR5LMNARORCSLC6A5 | |
| SCHEMBL6210622 | 0.90 | ELOVL6 (0.40) | NAMPTCCR5LMNAHSD17B10ELOVL6 | |
| SCHEMBL6211355 | 0.89 | LMNA (0.36) | LMNAHSD17B10ELOVL6SMYD3 | |
| SCHEMBL6211427 | 0.89 | ALDH1A1 (0.36) | LMNAHSD17B10CTSKSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |