Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210471 | 0.87 | LMNA (0.40) | DPP4NPC1RAB9ALMNA | |
| SCHEMBL6209599 | 0.87 | PLD2 (0.36) | DPP4DRD2DRD3 | |
| SCHEMBL6211807 | 0.85 | DPP4 (0.42) | DPP4CHRM4KDM4EALDH1A1POLB | |
| SCHEMBL6211156 | 0.85 | CHRM4 (0.41) | DPP4CHRM4DRD2DRD3 | |
| SCHEMBL6210811 | 0.81 | CHRM4 (0.40) | DPP4CHRM4KDM4EALDH1A1POLB | |
| SCHEMBL6211640 | 0.79 | KDM4E (0.33) | CHRM4KDM4EALDH1A1POLBNPC1 | |
| SCHEMBL6210722 | 0.79 | CHRM4 (0.42) | DPP4CHRM4 | |
| SCHEMBL6209845 | 0.79 | DPP4 (0.30) | DPP4NPC1 | |
| SCHEMBL6209435 | 0.78 | CTSK (0.42) | — | |
| SCHEMBL6210146 | 0.76 | CHRM2 (0.41) | DPP4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |