Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214307 | 0.85 | CTSK (0.31) | SMYD3 | |
| SCHEMBL6209599 | 0.80 | PLD2 (0.36) | DPP4 | |
| SCHEMBL6210471 | 0.80 | LMNA (0.40) | DPP4NPC1 | |
| SCHEMBL6209393 | 0.80 | CTSL (0.36) | SMYD3 | |
| SCHEMBL6209199 | 0.79 | — | — | |
| SCHEMBL6211627 | 0.79 | — | — | |
| SCHEMBL6209388 | 0.78 | CTSK (0.32) | SMYD3 | |
| SCHEMBL6211156 | 0.77 | CHRM4 (0.41) | DPP4 | |
| SCHEMBL6210999 | 0.75 | MAPK8 (0.30) | — | |
| SCHEMBL6209760 | 0.74 | MT-CO2 (0.33) | DPP4NPC1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |