Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094558 | 0.83 | ALDH1A1 (0.40) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6214920 | 0.71 | ERN1 (0.47) | LMNARECQLMEN1KMT2AERN1 | |
| SCHEMBL6798519 | 0.70 | LMNA (0.44) | LMNARECQLMEN1KMT2AMAPT | |
| SCHEMBL7097274 | 0.67 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL5142590 | 0.67 | MAPT (0.77) | RECQLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31236338 | 0.67 | MAPT (0.77) | RECQLMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7445763 | 0.66 | LMNA (0.69) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6212836 | 0.66 | ERN1 (0.42) | LMNARECQLMEN1KMT2AERN1 | |
| SCHEMBL6800731 | 0.65 | HTR2C (0.46) | MEN1KMT2AHTR2CALDH1A1POLB | |
| SCHEMBL12526432 | 0.64 | MAPT (0.67) | LMNARECQLMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2004-02-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | LMNA 4331/4885RECQL 2230/4885MEN1 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.