Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708084 | 0.88 | NPC1 (0.50) | FAAHACHEBCHENPC1MCHR1 | |
| SCHEMBL6229736 | 0.88 | NPC1 (0.45) | NPC1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6225469 | 0.88 | ACHE (0.46) | FAAHACHEBCHEMCHR1CHRM1 | |
| SCHEMBL6228504 | 0.84 | FAAH (0.49) | FAAHACHEBCHENPC1MCHR1 | |
| SCHEMBL6221960 | 0.83 | MCHR1 (0.57) | FAAHACHEBCHEMCHR1CHRM1 | |
| SCHEMBL6224697 | 0.82 | MCHR1 (0.57) | FAAHACHEBCHEMCHR1CHRM1 | |
| SCHEMBL6225433 | 0.81 | FAAH (0.50) | FAAHACHEBCHENPC1MCHR1 | |
| SCHEMBL6224439 | 0.80 | FAAH (0.47) | FAAHACHEBCHENPC1MCHR1 | |
| SCHEMBL6704716 | 0.79 | MCHR1 (0.52) | NPC1MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL6224507 | 0.79 | MCHR1 (0.48) | FAAHACHEBCHEMCHR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534689-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004024702-A1 | NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-25 | — | — | WO | disclosed |