Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227910 | 0.79 | MEN1 (0.43) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL6229784 | 0.79 | MEN1 (0.43) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL6224556 | 0.79 | MEN1 (0.43) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL10481523 | 0.72 | KDM4E (0.52) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL21082250 | 0.71 | PTGS1 (0.53) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL6225217 | 0.70 | LMNA (0.51) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL7159367 | 0.70 | PTGS1 (0.46) | SLC2A1PTGS1PTGS2HTTMEN1 | |
| SCHEMBL11401420 | 0.69 | GPR84 (0.45) | KDM4EDAO | |
| SCHEMBL31381374 | 0.69 | KDM4E (0.63) | PTGS1PTGS2MEN1KMT2AKDM4E | |
| SCHEMBL6520890 | 0.68 | HTR1D (0.55) | SLC2A1PTGS1PTGS2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651640-A1 | USE OF 7-FLUORO-1-METHYL-3-METHYLSULPHINYL-4-QUINOLONE IN THE TREATMENT OF ANGINA PECTORIS | Knoll AG (DE) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002144-A1 | USE OF 7-FLUORO-1-METHYL-3-METHYLSULPHINYL-4-QUINOLONE IN THE TREATMENT OF ANGINA PECTORIS | THE BOOTS COMPANY PLC (GB) | 1994-02-03 | — | — | WO | disclosed |