Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 10/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230126 | 0.94 | CTSD (0.44) | CTSDNPC1HTTRAB9AMAPT | |
| SCHEMBL4347491 | 0.88 | CTSD (0.40) | CTSDNPC1HTTRAB9AKDR | |
| SCHEMBL6223808 | 0.85 | CTSD (0.39) | CTSDNPC1HTTRAB9AMAPT | |
| SCHEMBL6230133 | 0.84 | CTSD (0.37) | CTSDKDRHDAC6NOTUM | |
| SCHEMBL4351090 | 0.83 | LMNA (0.41) | CTSDHTTRAB9AMAPTALDH1A1 | |
| SCHEMBL4347648 | 0.79 | GAA (0.38) | CTSDNPC1HTTRAB9AMAPT | |
| SCHEMBL6227570 | 0.78 | NPC1 (0.36) | CTSDNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6227080 | 0.77 | GAA (0.36) | CTSDNPC1HTTRAB9AMAPT | |
| SCHEMBL4346978 | 0.77 | MAPT (0.41) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL4350092 | 0.76 | CTSD (0.38) | CTSDNPC1HTTRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |