Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 11/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230126 | 0.87 | CTSD (0.44) | CTSDHDAC6NOTUMTRPV1 | |
| SCHEMBL4347491 | 0.86 | CTSD (0.40) | CTSDHDAC6NOTUMTRPV1KDR | |
| SCHEMBL6230128 | 0.84 | CTSD (0.39) | CTSDHDAC6NOTUMKDR | |
| SCHEMBL6223808 | 0.79 | CTSD (0.39) | CTSDHDAC6NOTUMALOX5EPHX2 | |
| SCHEMBL4349874 | 0.79 | GAA (0.33) | CTSDHDAC6 | |
| SCHEMBL4347648 | 0.77 | GAA (0.38) | CTSDHDAC6 | |
| SCHEMBL4351090 | 0.76 | LMNA (0.41) | CTSD | |
| SCHEMBL4350092 | 0.74 | CTSD (0.38) | CTSDHDAC6KDR | |
| SCHEMBL4346923 | 0.73 | SLC6A4 (0.43) | CTSDHDAC6MMP2MMP9 | |
| SCHEMBL4343453 | 0.73 | SMN1; SMN2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |